Passage
The Lord grant mercy unto the house of Onesiphorus: for he oft refreshed me, and was not ashamed of my chain;
The Lord grant mercy unto the house of Onesiphorus: for he oft refreshed me, and was not ashamed of my chain;
2 Timothy 1:14 That good thing which was committed unto [thee] guard through the Holy Spirit which dwelleth in us.
2 Timothy 1:15 This thou knowest, that all that are in Asia turned away from me; of whom are Phygelus and Hermogenes.
2 Timothy 1:16 The Lord grant mercy unto the house of Onesiphorus: for he oft refreshed me, and was not ashamed of my chain;
2 Timothy 1:17 but, when he was in Rome, he sought me diligently, and found me
2 Timothy 1:18 (the Lord grant unto him to find mercy of the Lord in that day); and in how many things he ministered at Ephesus, thou knowest very well.
The verse centers on "mercy", "lord", "grant", "house", "onesiphorus", "refreshed", "ashamed", and "chain". It is saying that the verse draws attention to "mercy" and "lord", so its meaning should be read from those terms before moving to application.
The nearby context moves from verse 15's "This thou knowest that all that are..." into verse 17's "but when he was in Rome he...", so "mercy" and "lord" belong inside that flow. In 2 Timothy context, the local focus is Christ, faith, and discipleship.
A plain takeaway is to answer the verse's own emphasis on "mercy" and "lord" with trust shaped by these words, not by a vague optimism outside the passage.