Passage
Little children, yet a little while I am with you. Ye shall seek me: and as I said unto the Jews, Whither I go, ye cannot come; so now I say unto you.
John 13:33 (ASV)
Nearby Context
John 13:31 When therefore he was gone out, Jesus saith, Now is the Son of man glorified, and God is glorified in him;
John 13:32 and God shall glorify him in himself, and straightway shall he glorify him.
John 13:33 Little children, yet a little while I am with you. Ye shall seek me: and as I said unto the Jews, Whither I go, ye cannot come; so now I say unto you.
John 13:34 A new commandment I give unto you, that ye love one another; even as I have loved you, that ye also love one another.
John 13:35 By this shall all men know that ye are my disciples, if ye have love one to another.
Study Lenses
The verse centers on "little", "children", "shall", "seek", "said", "jews", and "whither". It is saying that the verse draws attention to "little" and "children", so its meaning should be read from those terms before moving to application.
The nearby context moves from verse 32's "and God shall glorify him in himself..." into verse 34's "A new commandment I give unto you...", so "little" and "children" belong inside that flow. In John context, the local focus is the identity of Jesus, new birth, eternal life, and belief and unbelief.
A plain takeaway is to answer the verse's own emphasis on "little" and "children" with trust shaped by these words, not by a vague optimism outside the passage.