Passage
speaking lies in hypocrisy, cauterised as to their own conscience,
1 Timothy 4:2 (DBY)
Nearby Context
1 Timothy 4:1 But the Spirit speaks expressly, that in latter times some shall apostatise from the faith, giving their mind to deceiving spirits and teachings of demons
1 Timothy 4:2 speaking lies in hypocrisy, cauterised as to their own conscience,
1 Timothy 4:3 forbidding to marry, [bidding] to abstain from meats, which God has created for receiving with thanksgiving for them who are faithful and know the truth.
1 Timothy 4:4 For every creature of God [is] good, and nothing [is] to be rejected, being received with thanksgiving;
Study Lenses
The verse centers on "speaking", "lies", "hypocrisy", "cauterised", and "conscience". It is saying that the verse draws attention to "speaking" and "lies", so its meaning should be read from those terms before moving to application.
The nearby context moves from verse 1's "But the Spirit speaks expressly that in..." into verse 3's "forbidding to marry bidding to abstain from...", so "speaking" and "lies" belong inside that flow. In 1 Timothy context, the local focus is Christ, faith, and discipleship.
A plain takeaway is to answer the verse's own emphasis on "speaking" and "lies" with trust shaped by these words, not by a vague optimism outside the passage.