Passage
And I have profaned the princes of the sanctuary, and have given Jacob to the ban, and Israel to reproaches.
And I have profaned the princes of the sanctuary, and have given Jacob to the ban, and Israel to reproaches.
Isaiah 43:26 Put me in remembrance, let us plead together; rehearse thine own [cause], that thou mayest be justified.
Isaiah 43:27 Thy first father hath sinned, and thy mediators have rebelled against me.
Isaiah 43:28 And I have profaned the princes of the sanctuary, and have given Jacob to the ban, and Israel to reproaches.
The verse centers on "profaned", "princes", "sanctuary", "given", "jacob", "israel", and "reproaches". It is saying that the verse draws attention to "profaned" and "princes", so its meaning should be read from those terms before moving to application.
The prior verse says "Thy first father hath sinned and thy...", giving immediate footing for "profaned" and "princes". In Isaiah context, the local focus is the Holy One of Israel, judgment and restoration, the servant of the LORD, and Zion's hope.
A plain takeaway is to answer the verse's own emphasis on "profaned" and "princes" with trust shaped by these words, not by a vague optimism outside the passage.