Passage
They shall put you out of the synagogues; but the hour is coming that every one who kills you will think to render service to God;
They shall put you out of the synagogues; but the hour is coming that every one who kills you will think to render service to God;
John 16:1 These things I have spoken unto you that ye may not be offended.
John 16:2 They shall put you out of the synagogues; but the hour is coming that every one who kills you will think to render service to God;
John 16:3 and these things they will do because they have not known the Father nor me.
John 16:4 But I have spoken these things to you, that when their hour shall have come, ye may remember them, that I have said [them] unto you. But I did not say these things unto you from [the] beginning, because I was with you.
The verse centers on "shall", "synagogues", "hour", "coming", "kills", "think", "render", and "service". It is saying that the verse draws attention to "shall" and "synagogues", so its meaning should be read from those terms before moving to application.
The nearby context moves from verse 1's "These things I have spoken unto you..." into verse 3's "and these things they will do because...", so "shall" and "synagogues" belong inside that flow. In John context, the local focus is the identity of Jesus, new birth, eternal life, and belief and unbelief.
A plain takeaway is to answer the verse's own emphasis on "shall" and "synagogues" with trust shaped by these words, not by a vague optimism outside the passage.