Passage
On that day came to him Sadducees, who say there is no resurrection; and they demanded of him,
On that day came to him Sadducees, who say there is no resurrection; and they demanded of him,
Matthew 22:21 They say to him, Caesar's. Then he says to them, Pay then what is Caesar's to Caesar, and what is God's to God.
Matthew 22:22 And when they heard [him], they wondered, and left him, and went away.
Matthew 22:23 On that day came to him Sadducees, who say there is no resurrection; and they demanded of him,
Matthew 22:24 saying, Teacher, Moses said, If any one die, not having children, his brother shall marry his wife and shall raise up seed to his brother.
Matthew 22:25 Now there were with us seven brethren; and the first having married died, and not having seed, left his wife to his brother.
The verse centers on "came", "sadducees", "resurrection", and "demanded". It is saying that the verse draws attention to "came" and "sadducees", so its meaning should be read from those terms before moving to application.
The nearby context moves from verse 22's "And when they heard him they wondered..." into verse 24's "saying Teacher Moses said If any one...", so "came" and "sadducees" belong inside that flow. In Matthew context, the local focus is Christ, faith, and discipleship.
A plain takeaway is to answer the verse's own emphasis on "came" and "sadducees" with trust shaped by these words, not by a vague optimism outside the passage.