For I am sure that neither death, nor life, nor angels, nor principalities, nor powers, nor things present, nor things to come, nor might, Nor height, nor depth, nor any other creature, shall be able to separate us from the love of God which is in Christ Jesus our Lord.
Romans 8:36 (As it is written: For thy sake, we are put to death all the day long. We are accounted as sheep for the slaughter.)
Romans 8:37 But in all these things we overcome, because of him that hath loved us.
Romans 8:38 For I am sure that neither death, nor life, nor angels, nor principalities, nor powers, nor things present, nor things to come, nor might,
Romans 8:39 Nor height, nor depth, nor any other creature, shall be able to separate us from the love of God which is in Christ Jesus our Lord.
The verse centers on "sure", "neither", "death", "life", "angels", "principalities", "powers", and "things". It is saying that the verse draws attention to "sure" and "neither", so its meaning should be read from those terms before moving to application.
The prior verse says "But in all these things we overcome...", giving immediate footing for "sure" and "neither". In Romans context, the local focus is righteousness by faith, union with Christ, life in the Spirit, and God's covenant faithfulness.
A plain takeaway is to answer the verse's own emphasis on "sure" and "neither" with trust shaped by these words, not by a vague optimism outside the passage.