Passage
Therefore let them see and knowe, and let them consider and vnderstande together that the hand of the Lord hath done this, and the holy one of Israel hath created it.
Therefore let them see and knowe, and let them consider and vnderstande together that the hand of the Lord hath done this, and the holy one of Israel hath created it.
Isaiah 41:18 I will open riuers in the toppes of the hils, and fountaines in the middes of the valleis: I will make the wildernesse as a poole of water, and the waste land as springs of water.
Isaiah 41:19 I will set in the wildernesse the cedar, the shittah tree, and the mirre tree, and the pine tree, and I will set in the wildernesse the firre tree, the elme and the boxe tree together.
Isaiah 41:20 Therefore let them see and knowe, and let them consider and vnderstande together that the hand of the Lord hath done this, and the holy one of Israel hath created it.
Isaiah 41:21 Stand to your cause, saith the Lord: bring forth your strong reasons, saith ye King of Iaakob.
Isaiah 41:22 Let them bring foorth, and let them tell vs what shall come: let them shew the former things what they be, that wee may consider them, and knowe the latter ende of them: either declare vs things for to come.
The verse centers on "created", "therefore", "knowe", "consider", "vnderstande", "together", "hand", and "lord". It is saying that the verse draws attention to "created" and "therefore", so its meaning should be read from those terms before moving to application.
The nearby context moves from verse 19's "I will set in the wildernesse the..." into verse 21's "Stand to your cause saith the Lord...", so "created" and "therefore" belong inside that flow. In Isaiah context, the local focus is the Holy One of Israel, judgment and restoration, the servant of the LORD, and Zion's hope.
A plain takeaway is to answer the verse's own emphasis on "created" and "therefore" with trust shaped by these words, not by a vague optimism outside the passage.