Passage
For thornes there shall grow firre trees: for nettles shall growe the myrrhe tree, and it shalbe to the Lord for a name, and for an euerlasting signe that shall not be taken away.
Isaiah 55:13 (GNV)
Nearby Context
Isaiah 55:11 So shall my worde be, that goeth out of my mouth: it shall not returne vnto me voyde, but it shall accomplish that which I will, and it shall prosper in the thing whereto I sent it.
Isaiah 55:12 Therefore ye shall go out with ioy, and be led forth with peace: the mountaines and the hilles shall breake foorth before you into ioye, and all the trees of the fielde shall clap their handes.
Isaiah 55:13 For thornes there shall grow firre trees: for nettles shall growe the myrrhe tree, and it shalbe to the Lord for a name, and for an euerlasting signe that shall not be taken away.
Study Lenses
The verse centers on "thornes", "shall", "grow", "firre", "trees", "nettles", and "growe". It is saying that the verse draws attention to "thornes" and "shall", so its meaning should be read from those terms before moving to application.
The prior verse says "Therefore ye shall go out with ioy...", giving immediate footing for "thornes" and "shall". In Isaiah context, the local focus is the Holy One of Israel, judgment and restoration, the servant of the LORD, and Zion's hope.
A plain takeaway is to answer the verse's own emphasis on "thornes" and "shall" with trust shaped by these words, not by a vague optimism outside the passage.