Passage
always rejoice ye;
always rejoice ye;
1 Thessalonians 5:14 and we exhort you, brethren, admonish the disorderly, comfort the feeble-minded, support the infirm, be patient unto all;
1 Thessalonians 5:15 see no one evil for evil may render to any one, but always that which is good pursue ye, both to one another and to all;
1 Thessalonians 5:16 always rejoice ye;
1 Thessalonians 5:17 continually pray ye;
1 Thessalonians 5:18 in every thing give thanks, for this <FI>is<Fi> the will of God in Christ Jesus in regard to you.
The verse centers on "always" and "rejoice". It is saying that the verse draws attention to "always" and "rejoice", so its meaning should be read from those terms before moving to application.
The nearby context moves from verse 15's "see no one evil for evil may..." into verse 17's "continually pray ye...", so "always" and "rejoice" belong inside that flow. In 1 Thessalonians context, the local focus is Christ, faith, and discipleship.
A plain takeaway is to answer the verse's own emphasis on "always" and "rejoice" with trust shaped by these words, not by a vague optimism outside the passage.