Passage
The grace of our Lord Jesus Christ <FI>is<Fi> with your spirit! Amen.
The grace of our Lord Jesus Christ <FI>is<Fi> with your spirit! Amen.
Philemon 1:23 Salute thee doth Epaphras, (my fellow-captive in Christ Jesus,)
Philemon 1:24 Markus, Aristarchus, Demas, Lukas, my fellow-workmen!
Philemon 1:25 The grace of our Lord Jesus Christ <FI>is<Fi> with your spirit! Amen.
The verse centers on "Spirit", "grace", "lord", "jesus", "christ", and "amen". It is saying that salvation is received as God's gift through faith, so boasting is pushed out by the wording itself.
The prior verse says "Markus Aristarchus Demas Lukas my fellow-workmen...", giving immediate footing for "Spirit" and "grace". In Philemon context, the local focus is Christ, faith, and discipleship.
A plain takeaway is to answer the verse's own emphasis on "Spirit" and "grace" with trust shaped by these words, not by a vague optimism outside the passage.