Passage
marked out Son of God in power, according to [the] Spirit of holiness, by resurrection of [the] dead) Jesus Christ our Lord;
marked out Son of God in power, according to [the] Spirit of holiness, by resurrection of [the] dead) Jesus Christ our Lord;
Romans 1:2 (which he had before promised by his prophets in holy writings,)
Romans 1:3 concerning his Son (come of David's seed according to flesh,
Romans 1:4 marked out Son of God in power, according to [the] Spirit of holiness, by resurrection of [the] dead) Jesus Christ our Lord;
Romans 1:5 by whom we have received grace and apostleship in behalf of his name, for obedience of faith among all the nations,
Romans 1:6 among whom are *ye* also [the] called of Jesus Christ:
The verse centers on "Spirit", "marked", "power", "holiness", "resurrection", "dead", "jesus", and "christ". It is saying that the verse draws attention to "Spirit" and "marked", so its meaning should be read from those terms before moving to application.
The nearby context moves from verse 3's "concerning his Son come of David's seed..." into verse 5's "by whom we have received grace and...", so "Spirit" and "marked" belong inside that flow. In Romans context, the local focus is righteousness by faith, union with Christ, life in the Spirit, and God's covenant faithfulness.
A plain takeaway is to answer the verse's own emphasis on "Spirit" and "marked" with trust shaped by these words, not by a vague optimism outside the passage.